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MYP_051678
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Basic Information
85-102
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral assembly inhibition ▸ Assembly inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Standard
18 amino acids
C88H126N24O24S
Standard
Sequence
LYGNEGCGWAGWLLSPRG
Physicochemical Analysis
1936.15 Da
5.99
-0.25
-0.47
-0.0138
-0.18
0.20
0.24
27.73
70.56
0.1667
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
763.56
-6.22
28.0
25.0
57.0
137.0
6.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0319747 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Infection inhibition
Hepatitis C virus(J6/JFH1) | Huh-7.5 cells
20 μM
% inhibition
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
PaperPeptide inhibitors of hepatitis C virus core oligomerization and virus production. | Kota S, Coito C, Mousseau G, Lavergne JP, Strosberg AD. | J Gen Virol. 2009 Jun;90(Pt 6):1319-1328. | DOI:10.1099/vir.0.008565-0 | PMID:19264632 PMID19264632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19264632/
RECORD: Rec_0359717 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Hepatitis C virus (Oligomerization); Huh7.5
80 %
ELISA
PaperPeptide inhibitors of hepatitis C virus core oligomerization and virus production. | Kota S, Coito C, Mousseau G, Lavergne JP, Strosberg AD. | J Gen Virol. 2009 | PMID:19264632 PMID19264632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19264632/
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