Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC915H1453N251O251S9

DescriptionStandard

        PAALPVAQEPMLLLAITDFVANSATFTYFAAGALRKNISSDMIPKRFPLQLRTKSMGLYSPQLQELYPDQPMELQLSARRQPLLSCHHDDLHGILFGSAEAFVVLPNATRVPAFLLNIDASVTGKPAITRNRLRGTVRLTGPACPSQGSGAACPVLQVKRLENLLKFGLWLFGVPWANSECCPHPV
    

Molecular Weight20274.44 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)5.27

Net Charge (pH 7.4) 4.91

Charge Density (pH 7.0) 0.0283

GRAVY Index0.10

Hydrophobic Moment 0.61

Boman Index0.12

Instability Index67.23

Aliphatic Index 97.10

Aromaticity 0.0753

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7889.28

LogP -90.45

H-bond Donors 272.0

H-bond Acceptors 269.0

Rotatable Bonds 644.0

Heavy Atoms 1426.0

Ring Count 38.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109678 VERIFIED: NO

Provenance & Taxonomy

OrganismGalbula dea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria