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MYP_051622
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Basic Information
C4b(FIV ectodomain 774-777)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
4 amino acids
C28H44N8O5
Standard
Sequence
VRWI
Physicochemical Analysis
572.70 Da
9.72
0.73
0.52
0.1835
0.82
1.05
0.18
150.70
170.00
0.2500
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
228.31
0.54
9.0
6.0
16.0
41.0
2.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0026383 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
FIV-Pet(Feline immunodeficiency virus Pet):inhibition of virus replication in MBM cells
4.06 μg/mL
IC50
PaperPubMed PMID: 12610147 PMID12610147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12610147/
RECORD: Rec_0093659 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
FIV-M2(Feline immunodeficiency virus M2):inhibition of virus replication in MBM cells
7.8 μg/mL
IC50
PaperPubMed PMID: 12610147 PMID12610147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12610147/
RECORD: Rec_0114592 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0213431 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 12610147 PMID12610147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12610147/
RECORD: Rec_0243028 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-FIV Entry inhibition
FIV-M2 (Feline immunodeficiency virus M2) | MBM cells
7.8 μg/mL
IC50
Mammalian: 100 h; Yeast: >20 h; E. coli: >10 h
PaperAntiviral activity and conformational features of an octapeptide derived from the membrane-proximal ectodomain of the feline immunodeficiency virus transmembrane glycoprotein. | Giannecchini S, Di Fenza A, D'Ursi AM, Matteucci D, Rovero P, Bendinelli M. | J Virol. 2003 Mar;77(6):3724-33. | DOI:10.1128/jvi.77.6.3724-3733.2003 | PMID:12610147 PMID12610147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12610147/
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