Peptide Database

Peptide Name[des-Gln14]ghrelin

Function Ontology

Hormonal / Endocrine ▸ Hormonal activity

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Signaling peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC134H223N43O39

DescriptionStandard

        GSSFLSPEHQKAQRKESKKPPAKLQPR
    

Molecular Weight3060.47 Da

Isoelectric Point (pI)10.56

Net Charge (pH 7.0)4.85

Net Charge (pH 7.4) 4.58

Charge Density (pH 7.0) 0.1796

GRAVY Index-1.67

Hydrophobic Moment 0.42

Boman Index-0.45

Instability Index68.56

Aliphatic Index 36.30

Aromaticity 0.0370

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1352.13

LogP -16.33

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 104.0

Heavy Atoms 216.0

Ring Count 6.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022385 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]; Rattus norvegicus [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID10090;10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsThe third residue, a serine, is octanoylated.

Bio-Activity Profile

Function

Neuropeptide activity Signaling peptide

Targetghrelin receptor (Mouse); ghrelin receptor (Rat)

RECORD: Rec_0074437 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Metabolic regulation Hormonal activity

Targetmetabolic/glucose regulation; hormone receptor/system