Peptide Database

Peptide NameBeta-defensin 136 (Defensin, beta 136; Human, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC291H436N82O74S8

DescriptionStandard

        MFGNDGVKVRTCTSQKAVCFFGCPPGYRWIAFCHNILSCCKNMTRFQPPQAKDPWVH
    

Molecular Weight6523.60 Da

Isoelectric Point (pI)9.12

Net Charge (pH 7.0)4.61

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0809

GRAVY Index-0.21

Hydrophobic Moment 0.60

Boman Index0.03

Instability Index62.11

Aliphatic Index 46.14

Aromaticity 0.1404

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2482.21

LogP -23.14

H-bond Donors 90.0

H-bond Acceptors 89.0

Rotatable Bonds 202.0

Heavy Atoms 455.0

Ring Count 17.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208971 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0409880 VERIFIED: NO