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MYP_051502
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Basic Information
Fibrinogen Am1, FGG(398-413)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
16 amino acids
C90H152N22O22S
Standard
Sequence
YSLKKTSMKIIPFTRL
Physicochemical Analysis
1926.37 Da
10.46
3.76
3.55
0.2348
-0.05
0.42
-0.03
9.00
97.50
0.1250
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
732.14
-4.30
27.0
27.0
65.0
135.0
3.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0130508 VERIFIED: YES
Provenance & Taxonomy
American alligator [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID25671663 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25671663/
RECORD: Rec_0229119 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
2.84 μM
EC50
PMID25671663 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25671663/
RECORD: Rec_0247423 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus cereus ATCC 11778
9.35 μM
EC50
PMID25671663 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25671663/
RECORD: Rec_0300701 VERIFIED: YES
Provenance & Taxonomy
Alligator mississippiensis [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
0.332 μM
EC50
PaperBioprospecting the American Alligator (Alligator mississippiensis) Host Defense Peptidome.
RECORD: Rec_0315283 VERIFIED: YES
Provenance & Taxonomy
Alligator mississippiensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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