Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC498H805N153O141S3

DescriptionStandard

        QLPRRFPLQLTTKSMGVFSPQVGTGGVGHGDTGGIWGRTGHRRDGMQPLLSCRPDALHGALFASAEAFVVLPNATRVPAFLLNIDAEVTGKPTITRNRLGGTVRLAG
    

Molecular Weight11287.85 Da

Isoelectric Point (pI)11.42

Net Charge (pH 7.0)6.02

Net Charge (pH 7.4) 5.64

Charge Density (pH 7.0) 0.0563

GRAVY Index-0.08

Hydrophobic Moment 0.51

Boman Index0.06

Instability Index36.58

Aliphatic Index 84.77

Aromaticity 0.0561

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4659.12

LogP -52.69

H-bond Donors 164.0

H-bond Acceptors 153.0

Rotatable Bonds 362.0

Heavy Atoms 795.0

Ring Count 18.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066036 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptosomus discolor [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria