Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length191 amino acids

Chemical FormulaC941H1500N256O288S10

DescriptionStandard

        MEFKEIKMSVKQRLAAVGLSASLILAGGTLVAPWEGKENKAYKDVVGVWTQCYGNTNNVDRTKPKTDDQCDDELAKELVSYNKKMKKYVKVELTVGQEAAFTSFVYNVGEGTWQRGTPLKLLNEGKPVQACQFLMKYNKAGGKTYAGLTNRRKAEMEVCLGNNKEAIEEANRIFESYKDGDYIDIMSGGRL
    

Molecular Weight21328.17 Da

Isoelectric Point (pI)8.74

Net Charge (pH 7.0)3.48

Net Charge (pH 7.4) 3.13

Charge Density (pH 7.0) 0.0182

GRAVY Index-0.54

Hydrophobic Moment 0.73

Boman Index-0.07

Instability Index27.14

Aliphatic Index 73.51

Aromaticity 0.0890

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 30160.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8907.69

LogP -106.01

H-bond Donors 309.0

H-bond Acceptors 302.0

Rotatable Bonds 705.0

Heavy Atoms 1495.0

Ring Count 24.0

Amide Bonds 209.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205269 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudomonas phage PPSC2 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic