Peptide Database

Peptide NamePancreatic icosapeptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC95H147N29O31

DescriptionStandard

        DRGETLDILEWGSPHAAAPR
    

Molecular Weight2191.36 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-2.14

Net Charge (pH 7.4) -2.40

Charge Density (pH 7.0) -0.1072

GRAVY Index-0.76

Hydrophobic Moment 0.29

Boman Index-0.08

Instability Index22.48

Aliphatic Index 73.50

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 956.57

LogP -9.65

H-bond Donors 33.0

H-bond Acceptors 30.0

Rotatable Bonds 67.0

Heavy Atoms 155.0

Ring Count 5.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189107 VERIFIED: YES

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyNPY

Tax ID9685

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

NPY-family Neuropeptide Neuromodulator

RECORD: Rec_0219633 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0304113 VERIFIED: YES

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyPancreatic icosapeptide

Tax ID9685

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour