Peptide Database

Peptide NameDermaseptin-S11 (DRS-S11)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC378H598N98O121S3

DescriptionStandard

        MAFLKKSLFLVLFLGMVSLSICEEEKRENEDEEEQEDDEQSEEKRALWKTLLKGAGKVFGHVAKQFLGSQGQPES
    

Molecular Weight8547.57 Da

Isoelectric Point (pI)4.73

Net Charge (pH 7.0)-6.39

Net Charge (pH 7.4) -6.71

Charge Density (pH 7.0) -0.0852

GRAVY Index-0.59

Hydrophobic Moment 0.63

Boman Index-0.08

Instability Index71.74

Aliphatic Index 78.00

Aromaticity 0.0800

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3581.31

LogP -32.12

H-bond Donors 121.0

H-bond Acceptors 119.0

Rotatable Bonds 304.0

Heavy Atoms 600.0

Ring Count 9.0

Amide Bonds 80.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0200014 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagei [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetGram-negative and Gram-positive bacteria