Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC417H663N109O124S12

DescriptionStandard

        MKSFIAAVSLAVLLTFVCFQESSAVPVTEVHELEGTLTDDSPLPAELKMPVTSWKTLYDIRRKREASAAGCRFCCGCCGMSGCGVCCPF
    

Molecular Weight9572.16 Da

Isoelectric Point (pI)5.70

Net Charge (pH 7.0)-1.49

Net Charge (pH 7.4) -1.90

Charge Density (pH 7.0) -0.0167

GRAVY Index0.39

Hydrophobic Moment 0.52

Boman Index0.15

Instability Index64.66

Aliphatic Index 78.88

Aromaticity 0.0787

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3658.56

LogP -36.60

H-bond Donors 137.0

H-bond Acceptors 136.0

Rotatable Bonds 307.0

Heavy Atoms 662.0

Ring Count 14.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0206955 VERIFIED: NO

Provenance & Taxonomy

OrganismOryzias javanicus [Animal]

FamilyHepcidin

Tax ID123683

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0366455 VERIFIED: NO