Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length368 amino acids

Chemical FormulaC1823H2863N451O540S21

DescriptionStandard

        DQLSTLELNIQCGVVDIYVFMCSVSQMMAVWIQNKLKSTEFPEVRGGVDIGIGTVNYVISNMQVVQCSMSGQSMEFKQGTGVSVEVSQLSLAITGSWATQFGIIHDGGSFDLAVYNININTLLGLGDEAGRLSITTISCSDDIGGVHIQFHGGICPAIQQAISKLEMNLQKMPVSIPVNQYIYLSILFTSSPAVTDRSIELDIKGEFYSKSFPSEPPFSASAFDIKYAENYMLSLAASEFFVNSAAYAYLSSEVLQINITDNMIPKSFPFHLNTSQFGVFIPQVSMLCVQVMILEVKIDPVNLHKDASVLKHSLFVLNTLVQSYCYKLLTLTVGSSEIGDFKTAMLEQMLVIAVNRFVLPKLNGKNFK
    

Molecular Weight40411.29 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-9.75

Net Charge (pH 7.4) -10.44

Charge Density (pH 7.0) -0.0265

GRAVY Index0.31

Hydrophobic Moment 0.53

Boman Index0.22

Instability Index40.08

Aliphatic Index 102.96

Aromaticity 0.0951

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29255.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208557 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria