Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC372H605N91O101S6

DescriptionStandard

        MLSMLPVADMVKEFGVPVAVATTVAKIMEAADWLITGAMILAAIGTGGASLLAAAGKESLKAFLKKKYGEMGARAFTAW
    

Molecular Weight8160.72 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)1.51

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0191

GRAVY Index0.71

Hydrophobic Moment 0.63

Boman Index0.33

Instability Index12.34

Aliphatic Index 102.78

Aromaticity 0.0759

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2997.03

LogP -20.80

H-bond Donors 105.0

H-bond Acceptors 109.0

Rotatable Bonds 271.0

Heavy Atoms 570.0

Ring Count 10.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0097900 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus larvae subsp. pulvifaciens [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal