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MYP_051345
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Basic Information
c Mastoparan-C(cMP-C)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C78H144N20O18S2
Standard
Sequence
CLNLKALLAVAKKILC
Physicochemical Analysis
1714.23 Da
9.39
2.74
2.50
0.1711
1.43
0.58
0.31
22.84
183.12
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
620.97
-2.22
23.0
23.0
60.0
118.0
0.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0191419 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Candida albicans NCTC 1467
32 μM
MIC
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0219078 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Gram-positive bacteria: Staphylococcus aureus NCTC 10788
32 μM
MIC
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0227168 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Human glioblastoma U251-MG
8.56 μM
IC50
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0243345 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Candida albicans NCTC 1467
128 μM
MBC
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0255857 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Staphylococcus aureus NCTC 10788
64 μM
MBC
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
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