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MYP_051345
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Basic Information
c Mastoparan-C(cMP-C)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C78H144N20O18S2
Standard
Sequence
CLNLKALLAVAKKILC
Physicochemical Analysis
1714.23 Da
9.39
2.74
2.50
0.1711
1.43
0.58
0.31
22.84
183.12
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
620.97
-2.22
23.0
23.0
60.0
118.0
0.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009336 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Human breast adenocarcinoma MCF-7
13.66 μM
IC50
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0010176 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida albicans NCTC 1467
32 μM
MIC
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0031428 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Cancer:Human squamous lung carcinoma NCI-H157
7.02 μM
IC50
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0035232 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
horse RBCs
9.19 μM
HC50
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0058946 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Staphylococcus aureus ATCC 12493(MRSA
128 μM
MIC
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
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