Peptide Database

Peptide Name2'-5'-oligoadenylate synthase 1

Function Ontology

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length400 amino acids

Chemical FormulaC2074H3204N562O596S15

DescriptionStandard

        MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLAESNSADDETDDPRRYQKYGYIGTHEYPHFSHRPSTLQAASTPQAEEDWTCTIL
    

Molecular Weight46028.01 Da

Isoelectric Point (pI)8.51

Net Charge (pH 7.0)4.97

Net Charge (pH 7.4) 4.16

Charge Density (pH 7.0) 0.0124

GRAVY Index-0.49

Hydrophobic Moment 0.80

Boman Index-0.05

Instability Index44.12

Aliphatic Index 77.78

Aromaticity 0.1150

Extinction Coeff. Reduced 74830.00

Extinction Coeff. Oxidized 75455.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0271581 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyOAS

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsS-geranylgeranylation Cys397

Bio-Activity Profile

Function

Antiviral Replication inhibitor Translation regulator RNA-sensing effector Protein degradation regulator

TargetSARS-CoV-2