Peptide Database

Peptide NamePsdefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC184H321N61O56S7

DescriptionStandard

        VTCDLLSLQIKGIAINDSACAAHCLAMRRKGGSCKQGVCVCRN
    

Molecular Weight4508.35 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.41

Charge Density (pH 7.0) 0.0875

GRAVY Index0.30

Hydrophobic Moment 0.42

Boman Index0.02

Instability Index57.79

Aliphatic Index 95.35

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1905.84

LogP -24.26

H-bond Donors 73.0

H-bond Acceptors 68.0

Rotatable Bonds 155.0

Heavy Atoms 308.0

Ring Count 1.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348980 VERIFIED: NO

Provenance & Taxonomy

OrganismHolothuria glamberrima [Animal]; Protaetia brevitarsis seulensis [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-34; 20-39; 24-41

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0364165 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 18.6%, E 23.3%, T 32.6%, C 25.6% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antibacterial Antimicrobial

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