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MYP_051332
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Basic Information
Magainin-2 K(10)
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
33 amino acids
C174H300N50O39S
Standard
Sequence
GIGKFLHSAKKFGKAFVGEIMNSKKKKKKKKKK
Physicochemical Analysis
3748.62 Da
10.78
12.84
12.56
0.3890
-1.12
0.69
-0.33
2.96
50.30
0.0909
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1508.33
-11.75
53.0
54.0
146.0
264.0
4.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0243274 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
3.12 μg/mL
MIC
PMID1605597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1605597/
RECORD: Rec_0248594 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
25 μg/mL
MBC
PMID1605597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1605597/
RECORD: Rec_0268244 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
200 μg/mL
Hemolysis
PMID1605597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1605597/
RECORD: Rec_0295327 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 60.6%, E 0.0%, T 6.1%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0304385 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
1.57 μg/mL
MIC
PMID1605597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1605597/
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