Peptide Database

Peptide NameEsculentin-2-AJ4 antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC366H613N101O110S5

DescriptionStandard

        MLTLKKSMLLLFFLGTISLSLCEEERSADEDDGEKEVKRGILSLIKNAAKFVGKNLHKQAGKGGLEHLACKAKNEC
    

Molecular Weight8348.72 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)1.66

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0218

GRAVY Index-0.23

Hydrophobic Moment 0.71

Boman Index-0.03

Instability Index39.47

Aliphatic Index 97.63

Aromaticity 0.0395

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3437.47

LogP -31.79

H-bond Donors 121.0

H-bond Acceptors 119.0

Rotatable Bonds 302.0

Heavy Atoms 582.0

Ring Count 5.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0086753 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops [Animal]

Tax ID109940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0177475 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops jingdongensis [Animal]

FamilyEsculentin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial