Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length53 amino acids

Chemical FormulaC229H388N66O76S7

DescriptionStandard

        DFNLDLLSVSKKDSGASPRITSISLCTPGCKTGALMGCNMKTATCNCSIHVSK
    

Molecular Weight5506.38 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)2.80

Net Charge (pH 7.4) 2.46

Charge Density (pH 7.0) 0.0528

GRAVY Index0.05

Hydrophobic Moment 0.31

Boman Index0.04

Instability Index22.02

Aliphatic Index 75.47

Aromaticity 0.0189

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2283.78

LogP -31.95

H-bond Donors 85.0

H-bond Acceptors 87.0

Rotatable Bonds 185.0

Heavy Atoms 378.0

Ring Count 4.0

Amide Bonds 55.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018372 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis subsp. lactis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0242725 VERIFIED: NO