Peptide Database

Peptide NameBeta-defensin 40 (Protein Defb40; rodents, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC370H578N108O94S13

DescriptionStandard

        MKISCFLMLVLFLSCFQMNSGAGLDTMKCVRGKNNCHMHRCPWFFVLISTCYSGKGSCCQKRRWFTRSHVNNV
    

Molecular Weight8460.06 Da

Isoelectric Point (pI)9.58

Net Charge (pH 7.0)8.68

Net Charge (pH 7.4) 8.18

Charge Density (pH 7.0) 0.1189

GRAVY Index0.09

Hydrophobic Moment 0.43

Boman Index0.04

Instability Index52.50

Aliphatic Index 63.97

Aromaticity 0.1233

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3268.41

LogP -31.98

H-bond Donors 125.0

H-bond Acceptors 119.0

Rotatable Bonds 280.0

Heavy Atoms 585.0

Ring Count 15.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0092283 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0359936 VERIFIED: NO