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MYP_051275
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Basic Information
Hematopoietic antimicrobial peptide-37 [W2F,L29V], HFIAP-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C205H319N69O46
Standard
Sequence
GFFKKAWRKVKHAGRRVLDTAKGVGRHYVNNWLNRYR
Physicochemical Analysis
4486.16 Da
11.74
9.93
9.61
0.2683
-1.03
0.88
-0.33
20.43
60.54
0.1622
13980.00
13980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1928.62
-16.38
72.0
58.0
150.0
320.0
10.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0345505 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus epidermidis
02-4 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0371184 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Sheep erythrocytes
128 μg/mL
Hemolysis
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0378807 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Shigella sp.
8 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0382317 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC 13883
16 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0383926 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
W at position 7 and 32 are brominated
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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