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MYP_051275
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Basic Information
Hematopoietic antimicrobial peptide-37 [W2F,L29V], HFIAP-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C205H319N69O46
Standard
Sequence
GFFKKAWRKVKHAGRRVLDTAKGVGRHYVNNWLNRYR
Physicochemical Analysis
4486.16 Da
11.74
9.93
9.61
0.2683
-1.03
0.88
-0.33
20.43
60.54
0.1622
13980.00
13980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1928.62
-16.38
72.0
58.0
150.0
320.0
10.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0239564 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Streptococcus pyogenes
4 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0245316 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecium
04-8 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0245844 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
8 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0247418 VERIFIED: YES
Provenance & Taxonomy
Myxine glutinosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0259266 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Streptococcus pyogenes
16 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
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