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MYP_051275
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Basic Information
Hematopoietic antimicrobial peptide-37 [W2F,L29V], HFIAP-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C205H319N69O46
Standard
Sequence
GFFKKAWRKVKHAGRRVLDTAKGVGRHYVNNWLNRYR
Physicochemical Analysis
4486.16 Da
11.74
9.93
9.61
0.2683
-1.03
0.88
-0.33
20.43
60.54
0.1622
13980.00
13980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1928.62
-16.38
72.0
58.0
150.0
320.0
10.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184391 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 89.2%, E 0.0%, T 2.7%, C 8.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0197105 VERIFIED: YES
Provenance & Taxonomy
Atlantic hagfish [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
p. ATCC 29771, 43935, and 12290, S. sonnei, S. maltophilia, Salmonella Group B, Pseudomonas aeruginosa ATCC 27853, A. baumannii, Escherichia coli ATCC 25922, E. aerogenes, Enterobacter cloacae, Klebsiella pneumoniae
0.5-16
MIC
PaperHagfish intestinal antimicrobial peptides are ancient cathelicidins
RECORD: Rec_0209459 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Stenotrophomonas maltophilia
02-8 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0224953 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
8 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0238761 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacteroides sp. ATCC 12290
0.5-4 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
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