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MYP_051275
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Basic Information
Hematopoietic antimicrobial peptide-37 [W2F,L29V], HFIAP-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C205H319N69O46
Standard
Sequence
GFFKKAWRKVKHAGRRVLDTAKGVGRHYVNNWLNRYR
Physicochemical Analysis
4486.16 Da
11.74
9.93
9.61
0.2683
-1.03
0.88
-0.33
20.43
60.54
0.1622
13980.00
13980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1928.62
-16.38
72.0
58.0
150.0
320.0
10.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0078134 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
16 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0090923 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus epidermidis
64 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0107755 VERIFIED: YES
Provenance & Taxonomy
Atlantic hagfish [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
P. acnes ATCC 11827 and 33179, S. epidermidi, Streptococcus pyogenes, Enterococcus faecium, Staphylococcus aureus ATCC 29213, C. perfringens ATCC 9081 and 13124, Enterococcus faecalis
2-32 μM
MIC
PaperHagfish intestinal antimicrobial peptides are ancient cathelicidins
RECORD: Rec_0108396 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter baumannii
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
RECORD: Rec_0108850 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Shigella sonnei
02-4 μg/mL
MIC
PMID5019197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5019197/
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