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MYP_051211
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Basic Information
HTLV-II Rex (4-16)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C73H139N41O20S
Standard
Sequence
TRRQRTRRARRNRGC
Physicochemical Analysis
1943.21 Da
12.00
7.39
7.18
0.4925
-2.70
0.36
-1.37
139.30
6.67
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1092.56
-17.22
45.0
29.0
69.0
135.0
0.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009032 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Conjugation with Alexa 488 at glycyl cysteine sequence
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
RECORD: Rec_0065754 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Protein-derived CPP
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Fluorophore labeling
C-term detail: Alexa 488 labeling at glycyl cysteine sequence
Bio-Activity Profile
Cell-penetrating peptide
CHO-K1; HeLa; Jurkat
Fluorescence-based uptake assay
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
RECORD: Rec_0180487 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Conjugation with Alexa 488 at glycyl cysteine sequence
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
RECORD: Rec_0191987 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Alexa 488 labeling at glycyl cysteine sequence
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0219831 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Protein-derived CPP
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide
RAW 264.7
Fluorescence-based uptake assay
PMID11084031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11084031/
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