Peptide Database

Peptide NameL-cystatin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length133 amino acids

Chemical FormulaC652H1054N182O191S6

DescriptionStandard

        MEGYNILAVLIILVGVSMGQIPGGWIDANVGDTDVKEAARFATEAQSSRSNSLYHHKLLKIHKARTQVVSGINYEVFIETGTTTCKKSEVPLEDLKRCAVPENGVKHLCQAIVWVQAWIPRTKVTKLECQNKG
    

Molecular Weight14690.84 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)2.83

Net Charge (pH 7.4) 2.31

Charge Density (pH 7.0) 0.0212

GRAVY Index-0.12

Hydrophobic Moment 0.67

Boman Index0.05

Instability Index35.55

Aliphatic Index 96.69

Aromaticity 0.0602

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6013.52

LogP -57.74

H-bond Donors 211.0

H-bond Acceptors 204.0

Rotatable Bonds 494.0

Heavy Atoms 1031.0

Ring Count 19.0

Amide Bonds 144.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0300112 VERIFIED: YES

Provenance & Taxonomy

OrganismTachypleus tridentatus [Animal]

FamilyCystatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Protease inhibitor Thiol protease inhibitor Enzyme inhibitory Non-hemolytic

TargetGram-negative bacteria