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MYP_051199
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Basic Information
Histatin-2 (His-rich; Human, mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Standard
27 amino acids
C158H211N45O44
Standard
Sequence
RKFHEKHHSHREFPFYGDYGSNYLYDN
Physicochemical Analysis
3444.64 Da
7.10
0.11
-0.31
0.0041
-1.76
0.39
-0.30
38.45
14.44
0.2593
5960.00
5960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1458.45
-12.60
51.0
48.0
108.0
247.0
12.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027716 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Histatin
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperPubMed PMID: 1528633 PMID1528633 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1528633/
RECORD: Rec_0044649 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Histatin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
RECORD: Rec_0079666 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Histatin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PapermRNA Cloning, Evolutionary Analysis and Biological Characterization of Duck Avian Beta-defensin 10. Acta Veterinaria et Zootechnica Sinica, 2009, 40(9): 1320-1326 Evidence URLhttps://camp3.bicnirrh.res.in/seqDisp.php?id=CAMPSQ2887
RECORD: Rec_0200658 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperSugiyama K., Ogino T., Ogata K.;. "Rapid purification and characterization of histatins (histidine-rich polypeptides) from human whole saliva."; Arch. Oral Biol. 35:415-419. Evidence URLhttps://www.uniprot.org/uniprotkb/HIS1_HUMAN/entry
RECORD: Rec_0310764 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Histatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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