Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC353H573N109O95S9

DescriptionStandard

        MRILLFILGVLALLSITPPGRSSYFNAACPPRRHACRMKCNTNEYAVRYCDDSRICCRMKNVENKKNNKW
    

Molecular Weight8152.58 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)8.53

Net Charge (pH 7.4) 8.16

Charge Density (pH 7.0) 0.1218

GRAVY Index-0.36

Hydrophobic Moment 0.50

Boman Index-0.15

Instability Index67.94

Aliphatic Index 75.29

Aromaticity 0.0857

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3338.73

LogP -33.19

H-bond Donors 124.0

H-bond Acceptors 114.0

Rotatable Bonds 269.0

Heavy Atoms 566.0

Ring Count 12.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0091951 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence