Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length264 amino acids

Chemical FormulaC1342H2101N337O394S7

DescriptionStandard

        MEKPILKNMNEMLCPIITGEVEALNANLSMLEVLTKIDNYTILDYSLISSPEITENYVDLDLKGTFYPLENLTDPPFSPAPFVLPERSDSMLYVGISEYFFKSASFAYFTSGAFNVTLSTKEISSHLVRNSQGIGNVLSRVASTSVGLVILGQRLICSLSLNRFRLSLPESNRSNIEVLRFENILSSILHFGILPLANAKLQQGFPLPNPHKISFVNSDVEVLEHFILISTDLKYETSLKHPPSFHGWEGLNLISGQWKEKSAP
    

Molecular Weight29484.51 Da

Isoelectric Point (pI)5.40

Net Charge (pH 7.0)-6.95

Net Charge (pH 7.4) -7.57

Charge Density (pH 7.0) -0.0263

GRAVY Index0.05

Hydrophobic Moment 0.63

Boman Index0.14

Instability Index43.84

Aliphatic Index 104.47

Aromaticity 0.0947

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23045.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0284085 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinolophus ferrumequinum [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria