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MYP_051110
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Basic Information
hEP-2/deltaCys
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
32 amino acids
C172H301N59O46
Standard
Sequence
EELRVRLASHLRKLRKRLLRDADDLQKRLAVY
Physicochemical Analysis
3931.60 Da
10.87
4.93
4.70
0.1539
-0.79
0.78
-0.47
66.85
125.00
0.0312
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1775.51
-14.28
66.0
52.0
141.0
277.0
2.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0315372 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 84.4%, E 0.0%, T 0.0%, C 15.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0370888 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Apolipoprotein-derived
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cys deletion variant
Bio-Activity Profile
Antiviral Entry inhibitor
Hepatitis C virus (Virus entry); Huh7.5.1
10 μM
RT-PCR
PaperHuman apolipoprotein E peptides inhibit hepatitis C virus entry by blocking virus binding. | Liu S, McCormick KD, Zhao W, Zhao T, Fan D, Wang T. | Hepatology. 2012 | PMID:22334503 PMID22334503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22334503/
RECORD: Rec_0377071 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
5
PaperPubMed PMID: 22334503 PMID22334503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22334503/
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