Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length117 amino acids

Chemical FormulaC594H921N145O170S6

DescriptionStandard

        MLYIGIAEYFFKSASFAYFTAGAFNVTLSTKEISNHFVQNSQGLGNVLSRIAEIYILSQPFMVRIMATEPPVINLQPGNFTLDIPASIMMLTQPKNSTVETIVSMDFVSLGRQWSSL
    

Molecular Weight13005.93 Da

Isoelectric Point (pI)5.64

Net Charge (pH 7.0)-1.40

Net Charge (pH 7.4) -1.69

Charge Density (pH 7.0) -0.0120

GRAVY Index0.34

Hydrophobic Moment 0.63

Boman Index0.24

Instability Index32.15

Aliphatic Index 96.67

Aromaticity 0.1197

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5021.43

LogP -44.86

H-bond Donors 171.0

H-bond Acceptors 176.0

Rotatable Bonds 421.0

Heavy Atoms 915.0

Ring Count 22.0

Amide Bonds 129.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0345134 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence