Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC406H636N120O114S

DescriptionStandard

        MSQNPELIAQFSSGNQTRIKQGLTAKAPLEGWHYGPKEIVKKFQIHHRVAIEYGGSVYDIDNLRIVTPRLHDEIHYRR
    

Molecular Weight9054.19 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)2.94

Net Charge (pH 7.4) 2.45

Charge Density (pH 7.0) 0.0378

GRAVY Index-0.67

Hydrophobic Moment 0.54

Boman Index-0.09

Instability Index57.83

Aliphatic Index 85.00

Aromaticity 0.0897

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3795.20

LogP -34.53

H-bond Donors 131.0

H-bond Acceptors 123.0

Rotatable Bonds 301.0

Heavy Atoms 641.0

Ring Count 17.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0073487 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal