MYP_051057
Anoplin[5-9]
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
GLLKXIKTXL
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0420346
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
(S)-2-(4?-pentenyl)-alanine, O5-O9: stapled at 5,9; (S)-2-(4?-pentenyl)-alanine, O5-O9: stapled; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Bacillus subtilis 168
4 μM
MIC
RECORD: Rec_0422313
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
(S)-2-(4?-pentenyl)-alanine, O5-O9: stapled at 5,9; (S)-2-(4?-pentenyl)-alanine, O5-O9: stapled; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Hemolytic
Sheep RBC
64 μM
Hemolysis
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