‹ ›
MYP_051029
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
35 amino acids
C172H296N64O46S8
Standard
Sequence
LRDLVCYCRTRGCKRRERMNGTCRKGHLMYTLCCR
Physicochemical Analysis
4253.11 Da
9.86
7.79
7.44
0.2225
-0.72
0.43
-0.45
33.67
52.86
0.0571
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1847.48
-20.71
77.0
63.0
146.0
290.0
3.0
35.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0218158 VERIFIED: YES
Provenance & Taxonomy
Mus caroli [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0232592 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli. ALso killed Staphylococcus aureus based on virtual colony count assays (2.3 ug/ml killed 50%; 9.8 ug/ml killed 99.9%). This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h (Wang et al., 2023). The original was merged
PaperMouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.
RECORD: Rec_0244713 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]; Mammalia [Animal]
10090; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID6206053 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6206053/
RECORD: Rec_0245010 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 54.3%, T 20.0%, C 25.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0278900 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
1-6, 2-4, 3-5
Bio-Activity Profile
Antiparasitic Antimicrobial
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records on this page · Page 2 of 3