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MYP_051029
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
35 amino acids
C172H296N64O46S8
Standard
Sequence
LRDLVCYCRTRGCKRRERMNGTCRKGHLMYTLCCR
Physicochemical Analysis
4253.11 Da
9.86
7.79
7.44
0.2225
-0.72
0.43
-0.45
33.67
52.86
0.0571
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1847.48
-20.71
77.0
63.0
146.0
290.0
3.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0056059 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
9986
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20050260715A1/en PatentUS 2005/0260715 A1
RECORD: Rec_0099600 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
6-34; 8-23; 13-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML-35p
PaperPubMed PMID: 1500431 | PubMed PMID: 1500163 PMID1500431;1500163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1500431/
RECORD: Rec_0108582 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML-35p
PMID1500431;1500163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1500431/
RECORD: Rec_0110347 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
1-6, 2-4
Bio-Activity Profile
Antimicrobial Antiparasitic Antiamoebic
Entamoeba histolytica (HM1: IMSS)
4000 μg/mL
Microscopy (Trypan blue dye viability assay)
PMID22206022 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22206022/
RECORD: Rec_0172339 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes
PMID1500431;1500163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1500431/
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