Peptide Database

Peptide NameTHP-3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC106H171N33O26S4

DescriptionStandard

        CRKGSCHFGRCPIPLVKVGSCFG
    

Molecular Weight2451.96 Da

Isoelectric Point (pI)9.31

Net Charge (pH 7.0)3.81

Net Charge (pH 7.4) 3.49

Charge Density (pH 7.0) 0.1655

GRAVY Index0.26

Hydrophobic Moment 0.58

Boman Index0.06

Instability Index42.37

Aliphatic Index 59.13

Aromaticity 0.0870

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 930.92

LogP -10.05

H-bond Donors 37.0

H-bond Acceptors 35.0

Rotatable Bonds 77.0

Heavy Atoms 169.0

Ring Count 5.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0169244 VERIFIED: YES

Provenance & Taxonomy

OrganismTyto alba [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)