Peptide Database

Peptide NameBeta-Defensin 4 (8-41)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC160H266N48O40S6

DescriptionStandard

        CLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
    

Molecular Weight3694.51 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)6.78

Net Charge (pH 7.4) 6.43

Charge Density (pH 7.0) 0.1995

GRAVY Index-0.19

Hydrophobic Moment 0.52

Boman Index-0.06

Instability Index48.26

Aliphatic Index 57.35

Aromaticity 0.0588

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1395.05

LogP -14.27

H-bond Donors 54.0

H-bond Acceptors 54.0

Rotatable Bonds 118.0

Heavy Atoms 254.0

Ring Count 7.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015548 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 25923

Activity500 μg/mL

MethodMIC

RECORD: Rec_0107508 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0247467 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 33591

Activity500 μg/mL

MethodMIC

RECORD: Rec_0313804 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetKlebsiella pneumoniae ATCC 700603

Activity500 μg/mL

MethodMIC

RECORD: Rec_0372478 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa ATCC 22108

Activity500 μg/mL

MethodMIC