Peptide Database

Peptide NameT9F (Derived from RI16)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC102H185N39O17

DescriptionStandard

        RFRRLRKKFRKRLKKI
    

Molecular Weight2229.81 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)10.76

Net Charge (pH 7.4) 10.54

Charge Density (pH 7.0) 0.6722

GRAVY Index-1.80

Hydrophobic Moment 0.75

Boman Index-1.05

Instability Index66.97

Aliphatic Index 73.12

Aromaticity 0.1250

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1001.32

LogP -6.48

H-bond Donors 40.0

H-bond Acceptors 28.0

Rotatable Bonds 85.0

Heavy Atoms 158.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420685 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa ATCC 27853

Activity256 μM

MethodMIC

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