Peptide Database

Peptide NameAgaDef

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC193H297N61O53S6

DescriptionStandard

        ATCDLLSKWNWNHTACAAHCLARKYKGGYCNDKAVCVCRH
    

Molecular Weight4512.19 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)3.99

Net Charge (pH 7.4) 3.56

Charge Density (pH 7.0) 0.0999

GRAVY Index-0.34

Hydrophobic Moment 0.46

Boman Index-0.07

Instability Index29.58

Aliphatic Index 58.75

Aromaticity 0.1000

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1848.74

LogP -19.67

H-bond Donors 72.0

H-bond Acceptors 66.0

Rotatable Bonds 144.0

Heavy Atoms 313.0

Ring Count 9.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367740 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila bipectinata [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)