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MYP_050870
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Basic Information
Qna (De Novo Synthesis)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C88H124N26O13
Standard
Sequence
IHFKWRRWKFHI
Physicochemical Analysis
1754.09 Da
12.00
3.93
3.63
0.3277
-0.87
0.24
-0.17
130.37
65.00
0.3333
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
648.20
0.47
25.0
19.0
55.0
127.0
8.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0236707 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0270289 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococci faecalis ATCC 29212
64 μM
MIC
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0272404 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human blood cells
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0324363 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
hRBC >5%hemolysis
Hemolysis
PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0341887 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella Pulloru C79-13
32 μM
MIC
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
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