Peptide Database

Peptide NameHepcidin-1 (Hepcidin-1 protein)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC414H650N116O116S14

DescriptionStandard

        MRAFSIAVAVTLVLAFVCFVEALPFAGVPEPEEAGSNDTPVAAYPDMLAQSLMMPGHVREKRQSHLSMCRWCCNCCRGNKGCGPCCKF
    

Molecular Weight9557.21 Da

Isoelectric Point (pI)7.51

Net Charge (pH 7.0)0.60

Net Charge (pH 7.4) 0.13

Charge Density (pH 7.0) 0.0068

GRAVY Index0.24

Hydrophobic Moment 0.63

Boman Index0.12

Instability Index51.17

Aliphatic Index 68.75

Aromaticity 0.0795

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3632.59

LogP -35.51

H-bond Donors 132.0

H-bond Acceptors 133.0

Rotatable Bonds 302.0

Heavy Atoms 660.0

Ring Count 17.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027107 VERIFIED: NO

Provenance & Taxonomy

OrganismBoleophthalmus pectinirostris [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0056577 VERIFIED: NO