Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length397 amino acids

Chemical FormulaC2007H3122N498O586S12

DescriptionStandard

        MANISTNWEVKSPLFQDTGGADLFLSGVYFTGLLILTRNDFGHPTLQLQDCYSQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIITGEVEALNANLSMLEVLTKMDNYTLLDFSLLNAPEITENNIDLDLKGVFYPLENLADPPFPSVPFVLPERSDSMLYIGISEYFFKSASFAYFTAGAFNVTLSTKEISSHLVQNSQGVGNVLSRIAEIYILSQPFMIRIMATAPPVINLLPGNFTLDIPASIVILTQPENSTVETIVSMDFVASTSVGLVILGQRLICSLSLNRFRLTLPKSSRSNIEVLRFENILSFIIHFGILPLANAKLQQGFPLPNPHKISFVNSDIEVLEHFLLISTDLRYETSLKQQPSFHGWEGLNLISGQWSGNSAP
    

Molecular Weight43988.02 Da

Isoelectric Point (pI)4.85

Net Charge (pH 7.0)-15.77

Net Charge (pH 7.4) -16.52

Charge Density (pH 7.0) -0.0397

GRAVY Index0.21

Hydrophobic Moment 0.64

Boman Index0.20

Instability Index42.80

Aliphatic Index 107.05

Aromaticity 0.0982

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31525.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0029378 VERIFIED: NO

Provenance & Taxonomy

OrganismRousettus aegyptiacus (Egyptian rousette) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria