Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length150 amino acids

Chemical FormulaC743H1184N202O199S5

DescriptionStandard

        QLPRRFPLQLNTKSIGVFSPQLQELYPDQPMELQLSARRQPLLSCRPSALHGALFTSAEAFVVLPNATHVPAFLLNIDANVTGKPTITGNRLGGTVSLTGPLCQPLCQPHAGLRGLLVLQVKKLETLLKFGLWLFGVPWANSECGPHPVP
    

Molecular Weight16290.91 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)5.08

Net Charge (pH 7.4) 4.60

Charge Density (pH 7.0) 0.0339

GRAVY Index0.10

Hydrophobic Moment 0.54

Boman Index0.15

Instability Index53.09

Aliphatic Index 104.00

Aromaticity 0.0667

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6274.17

LogP -55.58

H-bond Donors 211.0

H-bond Acceptors 213.0

Rotatable Bonds 513.0

Heavy Atoms 1149.0

Ring Count 33.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017125 VERIFIED: NO

Provenance & Taxonomy

OrganismAtlantisia rogersi [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria