Peptide Database

Peptide NamepbtQ signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC134H226N34O38S2

DescriptionStandard

        MKKFALLFIALVTAVVISACGNQSTSSKG
    

Molecular Weight2985.56 Da

Isoelectric Point (pI)9.79

Net Charge (pH 7.0)2.49

Net Charge (pH 7.4) 2.25

Charge Density (pH 7.0) 0.0858

GRAVY Index0.90

Hydrophobic Moment 0.33

Boman Index0.31

Instability Index35.22

Aliphatic Index 111.03

Aromaticity 0.0690

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1163.74

LogP -12.06

H-bond Donors 42.0

H-bond Acceptors 43.0

Rotatable Bonds 101.0

Heavy Atoms 208.0

Ring Count 2.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0178438 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilyLipoprotein signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization CotA-laccase secretion Textile wastewater decolorization

TargetBacillus subtilis WB600

Activity23.7 U/mL

MethodLaccase activity assay

PaperGuan Z B, Shui Y, Song C M, et al. Efficient secretory production of CotA-laccase and its application in the decolorization and detoxification of industrial textile wastewater[J]. Environmental Science and Pollution Research, 2015, 22(12): 9515-9523. PMID25847445 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25847445/