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MYP_050726
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Basic Information
Cyclic Protegrin 1 [C6,15Acm-Cys][R4C,G17C], Cyclic PG-1 [C6,15Acm-Cys][R4C,G17C]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RGGCLXYCRRRFCVXVCR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0318653 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 6,15
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 29213
0.49 μM
MIC
PMID10824115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10824115/
RECORD: Rec_0335058 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 6,15
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis ATCC 29212
0.46 μM
MIC
PMID10824115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10824115/
RECORD: Rec_0360627 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 6,15
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida kefyr ATCC 37095
1.54 μM
MIC
PMID10824115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10824115/
RECORD: Rec_0389711 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 6,15
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 37092
8.22 μM
MIC
PMID10824115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10824115/
RECORD: Rec_0392247 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 6,15
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
4.1 μM
MIC
PMID10824115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10824115/
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