Peptide Database

Peptide NameEsculentin-1P

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC398H686N108O122S7

DescriptionStandard

        MFTTKKSMLLIVLLGMISLSLCEQKRDDDEEEGSETKRGIFSKLAGKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
    

Molecular Weight9160.81 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)2.48

Net Charge (pH 7.4) 2.19

Charge Density (pH 7.0) 0.0296

GRAVY Index-0.06

Hydrophobic Moment 0.59

Boman Index-0.00

Instability Index18.15

Aliphatic Index 103.21

Aromaticity 0.0238

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3755.73

LogP -35.35

H-bond Donors 134.0

H-bond Acceptors 132.0

Rotatable Bonds 335.0

Heavy Atoms 635.0

Ring Count 2.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198891 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

Tax ID8409

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal