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MYP_050693
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Basic Information
Killer peptide
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C39H71N11O15S2
Standard
Sequence
AKVTMTCSAS
Physicochemical Analysis
998.18 Da
8.27
0.79
0.58
0.0785
0.53
0.11
0.13
-10.86
49.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
432.16
-6.98
17.0
18.0
32.0
67.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0279492 VERIFIED: YES
Provenance & Taxonomy
Fungi [Fungus]
Killer peptide
4751;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Influenza A virus (Replication); LLC-MK2
2.686 μM
Hemagglutinin assay
PaperTherapeutic activity of an anti-idiotypic antibody-derived killer peptide against influenza A virus experimental infection. | Conti G, Magliani W, Conti S, Nencioni L, Sgarbanti R, Palamara AT, Polonelli L. | Antimicrob Agents Chemother. 2008 | PMID:18824612 PMID18824612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18824612/
RECORD: Rec_0283198 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HSV Replication inhibition
HSV-1 | Vero cells
50 μg/mL
% inhibition
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperAntiviral Activity of Synthetic Peptides Derived from Physiological Proteins. | Sala A, Ardizzoni A, Ciociola T, Magliani W, Conti S, Blasi E, Cermelli C | Intervirology. 2018;61(4):166-173. | DOI:10.1159/000494354 | PMID:30654366 PMID30654366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30654366/
RECORD: Rec_0315624 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Herpes simplex virus 1
PMID30654366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30654366/
RECORD: Rec_0378921 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Vesicular stomatitis virus
PMID30654366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30654366/
RECORD: Rec_0414231 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
Vero cells at the concentration of 100μg/ mL
PaperPubMed PMID: 30654366 PMID30654366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30654366/
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