Peptide Database

Peptide NameDefensin (Defensin 1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC368H593N115O102S12

DescriptionStandard

        MERSVRLFSTAFVFVLLLVATGMMGPMLAEGRTCESQSRKFKGACLSRSNCASVCQTEGFPGGHCRGFRRRCFCTKHC
    

Molecular Weight8645.13 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.60

Net Charge (pH 7.4) 7.16

Charge Density (pH 7.0) 0.0975

GRAVY Index0.02

Hydrophobic Moment 0.67

Boman Index-0.04

Instability Index61.19

Aliphatic Index 55.00

Aromaticity 0.0897

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3500.19

LogP -41.00

H-bond Donors 136.0

H-bond Acceptors 124.0

Rotatable Bonds 288.0

Heavy Atoms 597.0

Ring Count 11.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107554 VERIFIED: NO

Provenance & Taxonomy

OrganismPyrus pyrifolia [Plant]

FamilyDefensin

Tax ID3767

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic Non-ribosomal