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MYP_050594
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Basic Information
Palustrin-1c
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Hormonal / Endocrine ▸ Hormone peptide
Standard
27 amino acids
C125H228N36O34S3
Standard
Sequence
ALSILRGLEKLAKMGIALTNCKATKKC
Physicochemical Analysis
2875.56 Da
9.90
4.77
4.55
0.1768
0.30
0.84
0.03
19.90
115.93
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1153.00
-10.32
43.0
42.0
104.0
198.0
0.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005761 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
298395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
21-27
Bio-Activity Profile
Antimicrobial
Escherichia coli
28 μM
MIC
PaperMultiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris PMID11087945 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087945/
RECORD: Rec_0029384 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0147594 VERIFIED: YES
Provenance & Taxonomy
Rana palustris [Animal]
Palustrin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
28 μM
MIC
PMID11087945 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087945/
RECORD: Rec_0158274 VERIFIED: YES
Provenance & Taxonomy
Rana palustris [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
21-27
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
28 μM
MIC
PMID11087945 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087945/
RECORD: Rec_0172307 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
298395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
21-27
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
>150 μM
MIC
PaperMultiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris PMID11087945 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087945/
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